BackgroundAlthough the peer review process is believed to ensure scientific rigor, enhance research quality, and improve manuscript clarity, many investigators are concerned that the process is too slow, too expensive, too unreliable, and too static. In this feasibility study, we sought to survey corresponding authors of recently published clinical research studies on the speed and efficiency of the publication process.MethodsWeb-based survey of corresponding authors of a 20% random sample of clinical research studies in MEDLINE-indexed journals with Ovid MEDLINE entry dates (...) between December 1 and 15, 2016. Survey addressed perceived manuscript importance before first submission, approximate first submission and final acceptance dates, and total number of journal submissions, external peer reviews, external peer reviewers, and revisions requested, as well as whether authors would have considered publicly sharing their manuscript on an online platform instead of submitting to a peer-reviewed journal.ResultsOf 1780 surveys distributed, 27 corresponding authors opted out or requested that we stop emailing them and 149 emails failed (e.g., emails that bounced n = 64, returned with an away from office message n = 70, or were changed/incorrect n = 15), leaving 1604 respondents, of which 337 completed the survey (21.0%). Respondents and non-respondents were similar with respect to study type and publication journals’ impact factor, although non-respondent authors had more publications (p = 0.03). Among respondents, the median impact factor of the publications’ journal was 2.7 (interquartile range (IQR), 2.0–3.6) and corresponding authors’ median h-index and number of publications was 9 (IQR, 3–20) and 27 (IQR, 10–77), respectively. The median time from first submission to journal acceptance and publication was 5 months (IQR, 3–8) and 7 months (IQR, 5–12), respectively. Most respondents (62.0%, n = 209) rated the importance of their research as a 4 or 5 (5-point scale) prior to submission. Median number of journal submissions was 1 (IQR, 1–2), external peer reviews was 1 (IQR, 1–2), external peer reviewers was 3 (IQR, 2–4), and revisions requested was 1 (IQR, 1–1). Sharing manuscripts to a public online platform, instead of submitting to a peer-reviewed journal, would have been considered by 55.2% (n = 186) of respondents.ConclusionCorresponding authors have high perceptions of their research and reported requiring few manuscript submissions prior to journal acceptance, most commonly by lower impact factor journals. (shrink)

BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

© 2017. The American Astronomical Society. All rights reserved.We present new observations of the low-mass companion to HD 984 taken with the Gemini Planet Imager as a part of the GPI Exoplanet Survey campaign. Images of HD 984 B were obtained in the J and H bands. Combined with archival epochs from 2012 and 2014, we fit the first orbit to the companion to find an 18 au orbit with a 68% confidence interval between 14 and 28 au, an eccentricity (...) of 0.18 with a 68% confidence interval between 0.05 and 0.47, and an inclination of 119°with a 68% confidence interval between 114°and 125°. To address the considerable spectral covariance in both spectra, we present a method of splitting the spectra into low and high frequencies to analyze the spectral structure at different spatial frequencies with the proper spectral noise correlation. Using the split spectra, we compare them to known spectral types using field brown dwarf and low-mass star spectra and find a best-fit match of a field gravity M6.5 ±1.5 spectral type with a corresponding temperature of K. Photometry of the companion yields a luminosity of log=2.88 ± 0.07 dex with DUSTY models. Mass estimates, again from DUSTY models, find an age-dependent mass of 34 ±1 to 95 ±4 M Jup. These results are consistent with previous measurements of the object. (shrink)

Subjective language has attracted substantial attention in the recent literature in formal semantics and philosophy of language Subjective meaning: alternatives to relativism, De Gruyter, Berlin, pp 1–19, 2016; Lasersohn in Subjectivity and perspective in truth-theoretic semantics, Oxford University Press, Oxford, 2017; Vardomskaya in Sources of subjectivity, Ph.D. thesis, University of Chicago, IL, 2018; Zakkou in Faultless disagreement: a defense of contextualism in the realm of personal taste, Vittorio Klostermann, Frankfurt a. M., 2019b). Most current theories argue that Subjective Predicates, which (...) express matters of opinion, semantically differ from ordinary predicates, which express matters of fact. We will call this view “SP exceptionalism”. This paper addresses SP exceptionalism by scrutinizing the behavior of SPs in attitude reports, which, as we will argue, significantly constrains the space of analytical options and rules out some of the existing theories. As first noticed by Stephenson :487–525, 2007a; Towards a theory of subjective meaning, Ph.D. thesis, Massachusetts Institute of Technology, Cambridge, MA, 2007b), the most prominent reading of embedded SPs is one where they talk about the attitude holder’s subjective judgment. As is remarked sometimes :327–352, 2009; Pearson in J Semant 30:103–154, 2013a), this reading is not the only one: embedded SPs may also talk about someone else’s, non-local, judgment. We concentrate specifically on such cases and show that non-local judgment is possible if and only if SPs are used within a DP that is outside main predicate position and that entire DP is read de re. We demonstrate that the behavior of SPs in attitude reports does not differ from that of ordinary predicates: it follows from general constraints on intersective modification and intensional quantification Ways of scope taking, Springer, Dordrecht, pp 183–215, 1997; Musan in On the temporal interpretation of noun phrases, Garland, New York, 1997; Percus in Nat Lang Semant 8:173–229, 2000; Keshet in Good intensions: paving two roads to a theory of the de re/de dicto distinction, Ph.D. thesis, Massachusetts Institute of Technology, Cambridge, MA, 2008). We argue that this unexceptional behavior of SPs in fact has unexpected consequences for SP exceptionalism. Precisely because SPs have been argued to be semantically different from ordinary predicates, not all theories correctly predict these less-studied data: some overgenerate :691–706, 2007; Sæbø 2009) and some undergenerate Proceedings of Sinn und Bedeutung, vol 11, pp 433–447, 2007; Pearson 2013a). Out of the currently available theories, only relativist accounts :643–686, 2005; MacFarlane 2014; Bylinina in J Semant 34, 291–331, 2017; Coppock in Linguist Philos 41:125–164, 2018) predict the right interpretation, and only that interpretation. We thus present a novel empirical argument for relativism, and, more generally, formulate a constraint that has to be taken into consideration by any view that advocates SP exceptionalism. (shrink)

Perceptual disjunctivism is a controversial thesis about perception. One familiar characterization of the thesis maintains that there is no common epistemic kind that is present in both veridical and non-veridical cases of perception. For example, the good case, in which one sees a yellow lemon, and the bad case, in which one hallucinates a yellow lemon, share a specific first-person phenomenology, being indistinguishable from the first-person point of view; however, seeing a yellow lemon and hallucinating a yellow lemon do not, (...) according to the disjunctivist, share a common epistemic kind. There are two types of disjunctivism: epistemological vs. metaphysical. John McDowell, 243–255, 2011, Philosophical Explorations, 16, 259–279, 2013) has articulated, refined, and defended one kind of disjunctivism. Tyler Burge, 1–78, 2005, Philosophical Explorations, 13, 43–80, 2011) has objected to many forms of disjunctivism, arguing that they are all inconsistent with the proximality principle in the vision sciences. PP requires an ability-general kind in common between relevantly similar perceptual states, such as seeing a yellow lemon and hallucinating a yellow lemon, which disjunctivism denies. Against the background of this debate some analytic epistemologists, such as Michael Martin, Alan Millar, 176–198, 2007), Berit Brogaard, 46–73, 2011), Duncan Pritchard, and Heather Logue, 105–133, 2013) remain attracted to some version of disjunctivism. Brogaard and Pritchard each have gone on to articulate and defend a version. Pritchard’s, for example, defends epistemological disjunctivism. Martin, Millar, and Logue, by contrast, have defended the idea that the disjunctivist is right about something, but perhaps not wholly correct about the nature of perception. In what follows, I articulate and defend the view that an interesting kind of disjunctivism is to be found through a reading of the Nyāya School of classical Indian philosophy. I articulate a version of perceptual disjunctivism informed by Nyāya perceptual theory that is not derivable from any single Nyāya philosopher. The view I offer is inspired by work on disjunctivism both in Anglo-analytic philosophy and in Nyāya scholarship, such as by Dasti and Phillips, 535–540, 2010), Ganeri, 541–550, 2010), Dasti, 1–15, 2012), Phillips, Vaidya, 562–585, 2013), and Schiller, 1–18, 2019). Importantly, the causal account I offer is distinct from Grice’s single-factor causal theory of perception by crucially involving a multi-factor causal theory of perception. My work on Nyāya perceptual theory derives primarily from Jaysankar Shaw’s account of Nyāya on the sources of knowledge, which is distinct from Stephen Phillips’ well-known account of Nyāya epistemology. Shaw’s theory has been developed and refined through textual analysis and dialectical engagement with the twentieth century Nyāya Pundit Philosopher, Viśvabandhu Tarkatīrtha. Like other modern Nyāya scholars, such as B. K. Matilal, A. Chakrabarti, 1–8, 2010), M. Chadha, J. Ganeri, and S. Phillips, 104–113, 2001, 2012), J. Shaw’s account shows how Nyāya epistemology is a living and continuing form of Indian philosophy. My goal here is twofold. On the one hand, I articulate multi-factor causal disjunctivism and show how it can be applied to the McDowell-Burge debate over the viability of disjunctivism and naïve realism. On the other hand, I aim to start a cross-cultural epistemological conversation with those that have contributed to the Anglo-analytic debate in anthologies, such as Haddock and Macpherson, Byrne and Logue, and introductions, such as Soteriou. The hope is that a cross-cultural epistemological investigation into disjunctivism will lead to better epistemic theorizing about the nature of perception. (shrink)

We give a commentary on Newelski's suggestion or conjecture [8] that topological dynamics, in the sense of Ellis [3], applied to the action of a definable group $G(M)$ on its “external type space” $S_{G,\textit{ext}}(M)$, can explain, account for, or give rise to, the quotient $G/G^{00}$, at least for suitable groups in NIP theories. We give a positive answer for measure-stable (or $fsg$) groups in NIP theories. As part of our analysis we show the existence of “externally definable” generics of $G(M)$ (...) for measure-stable groups. We also point out that for $G$ definably amenable (in a NIP theory) $G/G^{00}$ can be recovered, via the Ellis theory, from a natural Ellis semigroup structure on the space of global $f$-generic types. (shrink)

Liberalizm i svoboda -- Restrikt︠s︡ionizm i ogranichenie -- Liberal-restrikt︠s︡ionizm i garmonicheskai︠a︡ t︠s︡ivilizat︠s︡ii︠a︡.

Walter Freeman's theory of nonlinear neurodynamics has had a major impact on brain dynamics in modern cognitive neuroscience. Steven Bressler's theory of neurocognitive networks follows from Freeman's work, and his empirical evidence for the coordination of cortical areas by phase-coupled beta rhythms in large-scale cognitive brain networks supports Freeman's ideas on nonlinear brain dynamics. Bressler's work, taking Freeman's concepts into the realm of cognitive neurodynamics, also supports Scott Kelso's theory of metastability in coordination dynamics. The aims of the present paper (...) are threefold: 1) to explore relevant concepts in Freeman's theoretical framework, 2) unify it and provide empirical support for it, and 3) explore its import for the study of consciousness. We take as our point of departure Bressler and Kelso's 2016 publication on cortical coordination dynamics and the Freeman-Kelso dialogue noted in the literature on this topic. In our view, Freeman's conceptual framework has great explanatory power. Its grounding in a dynamical systems approach to the study of brain function, and its incorporation of embodiment, make it relevant to the study of consciousness. Thus, with Freeman, we argue that the scientific understanding of consciousness must move beyond notions of computationalism and mental representations, to employ concepts of nonlinear brain dynamics and embodiment. (shrink)

В монографии рассматриваются интерпретативные стратегии деконструкции, их историко-философские истоки, а также их значение для постметафизического мышления. Для научных работников, студентов и аспирантов.

In examining Ennead VI 4[22], we find Plotinus in conflict with modern, i.e., Cartesian or Kantian, assumptions about the relation of soul and body and the identification of the self with the subject. Curiously, his images and exposition are more in tune with Twentieth Century notions such as wave and field. With these as keys, we are in a position to unlock the subtlety of Plotinus' analysis of the way soul and body are present together, with sensation structured through the (...) body and judgment coming from the soul. The problem of the self concerns not only the unity of the self in terms of body and soul, but also how the self is constituted in relation to other selves, both keeping its individuality and sharing its experiences at the same time. (shrink)

This paper reports the introduction of electronic handsets, like those used on the television show 'Who Wants To Be A Millionaire?' into the teaching of philosophical logic. Logic lectures can provide quite a formidable challenge for many students, occasionally to the point of making them ill. Our rationale for introducing handsets was threefold: to get the students thinking and talking about the subject in a public environment; to make them feel secure enough to answer questions in the lectures because the (...) system enabled them to do this anonymously; and to build their confidence about their learning by their being able to see how they were progressing in relation to the rest of the students in the class. We have achieved all of these and more. Our experience has revealed that the use of handsets encourages a more dynamic form of student interaction in an environment - the lecture - that can, in the wrong hands, be utterly enervating, but they also provide an opportunity for the lecturer to respond to students' difficulties at the time when they really matter. In this paper, we discuss our case of rapid adoption, our grounds for judging it a success, and what that success seems to have depended on. (shrink)

Работа предназначена для ученых и специалистов, преподавателей, аспирантов, слушателей, студентов, а также всех интересующихся рассматриваемой темой.

Among Plato's works, the Statesman is usually seen as transitional between the Republic and the Laws. This book argues that the dialogue deserves a special place of its own. Whereas Plato is usually thought of as defending unchanging knowledge, Dr Lane demonstrates how, by placing change at the heart of political affairs, Plato reconceives the link between knowledge and authority. The statesman is shown to master the timing of affairs of state, and to use this expertise in managing the conflict (...) of opposed civic factions. To this political argument corresponds a methodological approach which is seen to rely not only on the familiar method of 'division', but equally on the unfamiliar centrality of the use of 'example'. The demonstration that method and politics are interrelated transforms our understanding of the Statesman and its fellow dialogues. (shrink)

The aim of this report is to present an example of a multidisciplinary Indian-Swedish co-operation on ethics in health care. It is based on a conference held in Asia Plateau, Panchgani, Maharasthra, India in 1998. The emphasis is on ethical values that are important for consumers of health care and professionals, and also for different cultures in developed and developing countries. The importance of human dignity is stressed. Sixteen recommendations are given in an appendix.

The first comprehensive study of Nietzsche's earliest book, The Birth of Tragedy, this important volume by M. S. Silk and J. P. Stern examines the work in detail: its place in Nietzsche's philosophical career; its value as an account of ancient Greek culture; its place in the history of German ideas, and its value as a theory of tragedy and music. Presented in a fresh twenty-first-century series livery, and including a specially commissioned preface written by Lesley Chamberlain, illuminating its enduring (...) importance and relevance to philosophical enquiry, this accessible study has been revived for a new generation of readers. (shrink)

t. 1. A-D -- t. 2. E-M -- t. 3. N-S -- t.4. T-I︠A︡.